Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study

Autor: Abhijit Sen, J. Ramón Quirós, Anette Hjartåker, Petra H.M. Peeters, Pietro Ferrari, H. B. Bueno-De-Mesquita, Ada Tosovic, María José Sánchez, Françoise Clavel-Chapelon, Eiliv Lund, Paolo Vineis, Martin Almquist, Kay-Tee Khaw, Valeria Pala, Naomi E. Allen, Pagona Lagiou, Aurelio Barricarte Gurrea, Marc J. Gunter, Christina C. Dahm, Kim Overvad, Antonio Agudo, Julie A. Schmidt, Marie-Christine Boutron-Ruault, Isabelle Romieu, Salvatore Panico, Paul N. Appleby, Christos Tsironis, Rosario Tumino, Verena A. Katze, Larraitz Arriola, Antonia Trichopoulou, Diana Gavrila, Heiner Boeing, Agnetha Linn Rostgaard-Hansen, Laura Baglietto, Elio Riboli, Silvia Franceschi, Nicholas J. Wareham, Elisabete Weiderpass, Maria Sandström, Konstantinos K. Tsilidis, Sabina Rinaldi, Domenico Palli, Tilman Kühn, Anne Tjønneland, Joakim Hennings, Raul Zamora-Ros
Přispěvatelé: Sen, Abhijit, Tsilidis, Konstantinos K, Allen, Naomi E, Rinaldi, Sabina, Appleby, Paul N, Almquist, Martin, Schmidt, Julie A, Dahm, Christina C, Overvad, Kim, Tjønneland, Anne, Rostgaard Hansen, Agnetha L, Clavel Chapelon, Françoise, Baglietto, Laura, Boutron Ruault, Marie Christine, Kühn, Tilman, Katze, Verena A, Boeing, Heiner, Trichopoulou, Antonia, Tsironis, Christo, Lagiou, Pagona, Palli, Domenico, Pala, Valeria, Panico, Salvatore, Tumino, Rosario, Vineis, Paolo, Bueno de Mesquita, Hb A, Peeters, Petra H, Hjartåker, Anette, Lund, Eiliv, Weiderpass, Elisabete, Quirós, J. Ramón, Agudo, Antonio, Sánchez, María José, Arriola, Larraitz, Gavrila, Diana, Gurrea, Aurelio Barricarte, Tosovic, Ada, Hennings, Joakim, Sandström, Maria, Romieu, Isabelle, Ferrari, Pietro, Zamora Ros, Raul, Khaw, Kay Tee, Wareham, Nicholas J, Riboli, Elio, Gunter, Marc, Franceschi, Silvia
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Male
Cancer Research
Epidemiology
Risk Factors
Cigarette-smoking
Prospective cohort study
education.field_of_study
Hazard ratio
Cohort
Public Health
Global Health
Social Medicine and Epidemiology
Middle Aged
European Prospective Investigation into Cancer and Nutrition
Oncology
Female
Life Sciences & Biomedicine
Human
prospective study
Adult
medicine.medical_specialty
Alcohol Drinking
alcohol consumption
Population
Lower risk
Pooled analysis
Thyroid carcinoma
Internal medicine
medicine
Humans
Women
Oncology & Carcinogenesis
Thyroid Neoplasms
Sex Distribution
education
Nutrition
Proportional Hazards Models
Gynecology
Science & Technology
Proportional hazards model
business.industry
Risk Factor
lifetime exposure
thyroid carcinoma
United States
Diet
Folkhälsovetenskap
global hälsa
socialmedicin och epidemiologi
Proportional Hazards Model
Trends
business
Body mass index
Cancer incidence
Zdroj: Sen, A, Tsilidis, K K, Allen, N E, Rinaldi, S, Appleby, P N, Almquist, M, Schmidt, J A, Dahm, C C, Overvad, K, Tjønneland, A, Rostgaard-Hansen, A L, Clavel-Chapelon, F, Baglietto, L, Boutron-Ruault, M-C, Kühn, T, Katze, V A, Boeing, H, Trichopoulou, A, Tsironis, C, Lagiou, P, Palli, D, Pala, V, Panico, S, Tumino, R, Vineis, P, Bueno-de-Mesquita, H A, Peeters, P H, Hjartåker, A, Lund, E, Weiderpass, E, Quirós, J R, Agudo, A, Sánchez, M-J, Arriola, L, Gavrila, D, Gurrea, A B, Tosovic, A, Hennings, J, Sandström, M, Romieu, I, Ferrari, P, Zamora-Ros, R, Khaw, K-T, Wareham, N J, Riboli, E, Gunter, M & Franceschi, S 2015, ' Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study ', B J C, vol. 113, no. 5, pp. 840-7 . https://doi.org/10.1038/bjc.2015.280
Sen, A, Tsilidis, K K, Rinaldi, S, Appleby, P N, Almquist, M, Schmidt, J A, Dahm, C C, Overvad, K, Tjonneland, A, Rostgaard-Hansen, A L, Clavel-Chapelon, F, Baglietto, L, Boutron-Ruault, M C, Kuhn, T, Katze, V A, Boeing, H, Trichopoulou, A, Tsironis, C, Lagiou, P, Palli, D, Pala, V, Panico, S, Tumino, R, Vineis, P, Bueno-de-Mesquita, H A, Peeters, P H, Hjartaker, A, Lund, E, Weiderpass, E, Quiros, J R, Agudo, A, Sanchez, M J, Arriola, L, Gavrila, D, Gurrea, A B, Tosovic, A, Hennings, J, Sandstrom, M, Romieu, I, Ferrari, P, Zamora-Ros, R, Khaw, K T, Wareham, N J, Riboli, E, Gunter, M & Franceschi, S 2015, ' Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study ', British Journal of Cancer, vol. 113, no. 5, pp. 840-7 . https://doi.org/10.1038/bjc.2015.280
British Journal of Cancer
British Journal of Cancer, 113(5), 840. Nature Publishing Group
ISSN: 0007-0920
Popis: BACKGROUND: Results from several cohort and case-control studies suggest a protective association between current alcohol intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain unanswered.METHODS: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid carcinoma was examined in the European Prospective Investigation into Cancer and Nutrition. Among 477 263 eligible participants (70% women), 556 (90% women) were diagnosed with differentiated thyroid carcinoma over a mean follow-up of 11 years. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using multivariable Cox proportional hazards models.RESULTS: Compared with participants consuming 0.1-4.9 g of alcohol per day at recruitment, participants consuming 15 or more grams (approximately 1-1.5 drinks) had a 23% lower risk of differentiated thyroid carcinoma (HR=0.77; 95% CI=0.60-0.98). These findings did not differ greatly when analyses were conducted for lifetime alcohol consumption, although the risk estimates were attenuated and not statistically significant anymore. Similar results were observed by type of alcoholic beverage, by differentiated thyroid carcinoma histology or according to age, sex, smoking status, body mass index and diabetes.CONCLUSIONS: Our study provides some support to the hypothesis that moderate alcohol consumption may be associated with a lower risk of papillary and follicular thyroid carcinomas.British Journal of Cancer advance online publication, 27 August 2015; doi:10.1038/bjc.2015.280 www.bjcancer.com.
Databáze: OpenAIRE
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