SARS-CoV-2 Infection in Health Care Personnel and Their Household Contacts at a Tertiary Academic Medical Center: Protocol for a Longitudinal Cohort Study
Autor: | Elle Law, Raquel Reyes, Deanna Zhu, Allison E. Aiello, Elise King, Subhashini A. Sellers, Meghan E. Rebuli, Evans K Lodge, Cherese Beatty, Suemin Chung, Jonathan J. Juliano, Naseem Alavian, Haley E Garrett, Ross M. Boyce, Haley Abernathy, Alexander Volfovsky, Paul N. Zivich, Jasmine L Taylor, Jason Xu, Emily J Ciccone, Alena J. Markmann, Elyse M. Miller, David J. Weber |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Population Computer applications to medicine. Medical informatics R858-859.7 health personnel 01 natural sciences Occupational safety and health 03 medical and health sciences 0302 clinical medicine cohort studies Health care medicine Protocol Bluetooth contact tracking 030212 general & internal medicine 0101 mathematics education Prospective cohort study Personal protective equipment education.field_of_study mobile phone seroprevalence business.industry SARS-CoV-2 010102 general mathematics COVID-19 General Medicine survey-based research Family medicine Cohort occupational health Medicine Observational study business Cohort study |
Zdroj: | JMIR Research Protocols, Vol 10, Iss 4, p e25410 (2021) JMIR Research Protocols |
ISSN: | 1929-0748 |
Popis: | Background Health care personnel (HCP) are at high risk for exposure to the SARS-CoV-2 virus. While personal protective equipment (PPE) may mitigate this risk, prospective data collection on its use and other risk factors for seroconversion in this population is needed. Objective The primary objectives of this study are to (1) determine the incidence of, and risk factors for, SARS-CoV-2 infection among HCP at a tertiary care medical center and (2) actively monitor PPE use, interactions between study participants via electronic sensors, secondary cases in households, and participant mental health and well-being. Methods To achieve these objectives, we designed a prospective, observational study of SARS-CoV-2 infection among HCP and their household contacts at an academic tertiary care medical center in North Carolina, USA. Enrolled HCP completed frequent surveys on symptoms and work activities and provided serum and nasal samples for SARS-CoV-2 testing every 2 weeks. Additionally, interactions between participants and their movement within the clinical environment were captured with a smartphone app and Bluetooth sensors. Finally, a subset of participants’ households was randomly selected every 2 weeks for further investigation, and enrolled households provided serum and nasal samples via at-home collection kits. Results As of December 31, 2020, 211 HCP and 53 household participants have been enrolled. Recruitment and follow-up are ongoing and expected to continue through September 2021. Conclusions Much remains to be learned regarding the risk of SARS-CoV-2 infection among HCP and their household contacts. Through the use of a multifaceted prospective study design and a well-characterized cohort, we will collect critical information regarding SARS-CoV-2 transmission risks in the health care setting and its linkage to the community. International Registered Report Identifier (IRRID) DERR1-10.2196/25410 |
Databáze: | OpenAIRE |
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