Investigation of THz Absorptive Signatures in Opioids
| Autor: | Weidong Zhang, Alexei Bykhovski, Elliott R. Brown |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Fluid Flow and Transfer Processes
spectroscopy Technology QH301-705.5 Process Chemistry and Technology Physics QC1-999 General Engineering opioids oxycodone Engineering (General). Civil engineering (General) fentanyl Computer Science Applications sensing molecular dynamics modeling THz Chemistry General Materials Science TA1-2040 Biology (General) Instrumentation QD1-999 |
| Zdroj: | Applied Sciences, Vol 12, Iss 61, p 61 (2022) Applied Sciences; Volume 12; Issue 1; Pages: 61 |
| ISSN: | 2076-3417 |
| Popis: | We investigate the possibility of sensing opioid drugs, such as fentanyl, by their THz electromagnetic signatures. The methods include both computer modeling and experiments. Molecular dynamics simulations predict that fentanyl should display THz resonances, with several of them occurring below 1.0 THz; the lowest one is at around 0.337 THz (337 GHz). Spectroscopy measurements were conducted on oxycodone, which was used as a surrogate for fentanyl. They display vibrational absorption resonances between ∼1.4 and 1.6 THz. |
| Databáze: | OpenAIRE |
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