Transarterial chemoembolisation in intermediate-stage hepatocellular carcinoma. Survey on clinical practice in hospitals in the Madrid Region
| Autor: | Mar Lozano-Maya, Francisco Gea-Rodríguez, Benjamín Polo-Lorduy, Leticia González-Moreno, María Trapero-Marugán, Raquel González-Alonso, José María Ladero-Quesada, Ana Matilla Peña, Jose Luis Lledo-Navarro, Belén Piqueras-Alcol, Fernando Pons-Renedo, Elvira Poves-Martínez, Mariano Gómez-Rubio, Ana María Martín-Algívez, Óscar Núñez-Martínez, Alberto Ibáñez-Pinto, Antonio Díaz-Sánchez, Conrado M. Fernández-Rodríguez |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Carcinoma Hepatocellular Time Factors Lipiodol Specialties of internal medicine Computed tomography Intermediate stage Surveys and Questionnaires medicine Humans Chemoembolization Therapeutic Practice Patterns Physicians' Neoplasm Staging Hepatology Drug eluting beads medicine.diagnostic_test Treatment regimen business.industry General surgery Liver Neoplasms Drug-eluting beads General Medicine medicine.disease Hospitals Surgery Clinical Practice Treatment Outcome RC581-951 Spain Health Care Surveys Hepatocellular carcinoma Radiological weapon Practice Guidelines as Topic Neoplasm staging Guideline Adherence business Barcelona Clinic Liver Cancer System |
| Zdroj: | Annals of Hepatology, Vol 14, Iss 2, Pp 207-217 (2015) |
| ISSN: | 1665-2681 |
| Popis: | Background. Transarterial chemoembolisation (TACE), having demonstrated survival benefits, is the treatment of choice in intermediate-stage hepatocellular carcinoma, although there is great heterogeneity in its clinical application. Material and methods. A survey was sent to the Madrid Regional hospitals to assess applicability, indications and treatment protocols. The assessment was made overall and according to the type of hospital (groups A vs. B and C). Results. Seventeen out of 22 hospitals responded (8/8 group A, 9/ 14 group B-C). All do/indicate transarterial chemoembolisation, 13/17 at their own facilities. Eight of the 17 hospitals have multidisciplinary groups (5/8 A, 3/9 B-C). Nine hospitals perform > 20 procedures/year (7 group A), and 6 from group B-C request/perform < 10/year. It is performed on an “on-demand” basis in 12/17. In 5 hospitals, all the procedures use drug-eluting beads loaded with doxorubicin. The average number of procedures per patient is 2. The mean time from diagnosis of hepatocellular carcinoma to transarterial chemoembolisation is ≤ 2 months in 16 hospitals. In 11/17 hospitals, response is assessed by computed tomography. Radiological response is measured without specific criteria in 12/17 and the other five hospitals (4 group A) assessed using standardised criteria. Conclusion. Uniformity among the Madrid Regional hospitals was found in the indication and treatment regimen. The use of DEB-TACE has become the preferred form of TACE in clinical practice. The differentiating factors for the more specialised hospitals are a larger volume of procedures, decision-making by multidisciplinary committees and assessment of radiological response more likely to be standardised. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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