Corticosteroid use in otolaryngology: current considerations during the COVID-19 era
| Autor: | C.W. David Chang, Edward D. McCoul, Selena E. Briggs, Elizabeth A. Guardiani, Marlene L. Durand, Tessa A. Hadlock, Alexander T. Hillel, Nrusheel Kattar, Peter J.M. Openshaw, Nosayaba Osazuwa‐Peters, David M. Poetker, Jennifer J. Shin, Sujana S. Chandrasekhar, Carol R. Bradford, Michael J. Brenner |
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| Přispěvatelé: | National Institute for Health Research, UKRI MRC COVID-19 Rapid Response Call, UK Research and Innovation |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
vomiting
coronavirus facial paralysis laryngotracheal stenosis CHRONIC RHINOSINUSITIS head and neck Otolaryngology NECK-CANCER vaccine AMERICAN ACADEMY nasal polyposis osteoradionecrosis ERAS SENSORINEURAL HEARING-LOSS chemoradiation Child tonsillectomy adenoid FLUTICASONE PROPIONATE steroid RANDOMIZED CONTROLLED-TRIAL nausea Bell palsy sudden sensorineural hearing loss posterior glottic stenosis subglottic stenosis Life Sciences & Biomedicine corticosteroid COVID-19 Vaccines ENHANCED RECOVERY sinusitis UNITED-STATES tracheostomy severe acute respiratory syndrome sinonasal INTRALESIONAL STEROID INJECTION interleukin 4 dupilumab Bell's palsy cancer Humans rhinology perioperative rhinosinusitis hearing loss Science & Technology SARS-CoV-2 COVID-19 otitis media 1103 Clinical Sciences Bell’s palsy vaccination radiation mRNA vaccine pediatric Otorhinolaryngology facia palsy enhanced recovery after surgery inflammation Surgery edema |
| Popis: | Objective: To offer pragmatic, evidence-informed advice on administering corticosteroids in otolaryngology during the coronavirus disease 2019 (COVID-19) pandemic, considering therapeutic efficacy, potential adverse effects, susceptibility to COVID-19, and potential effects on efficacy of vaccination against SARS-CoV-2, which causes COVID-19. Data Sources: PubMed, Cochrane Library, EMBASE, CINAHL, and guideline databases. Review Methods: Guideline search strategies, supplemented by database searches on sudden sensorineural hearing loss (SSNHL), idiopathic facial nerve paralysis (Bell’s palsy), sinonasal polyposis, laryngotracheal disorders, head and neck oncology, and pediatric otolaryngology, prioritizing systematic reviews, randomized controlled trials, and COVID-19–specific findings. Conclusions: Systemic corticosteroids (SCSs) reduce long-term morbidity in individuals with SSNHL and Bell’s palsy, reduce acute laryngotracheal edema, and have benefit in perioperative management for some procedures. Topical or locally injected corticosteroids are preferable for most other otolaryngologic indications. SCSs have not shown long-term benefit for sinonasal disorders. SCSs are not a contraindication to vaccination with COVID-19 vaccines approved by the US Food and Drug Administration. The Centers for Disease Control and Prevention noted that these vaccines are safe for immunocompromised patients. Implications for Practice: SCS use for SSNHL, Bell’s palsy, laryngotracheal edema, and perioperative care should follow prepandemic standards. Local or topical corticosteroids are preferable for most other otolaryngologic indications. Whether SCSs attenuate response to vaccination against COVID-19 or increase susceptibility to SARS-CoV-2 infection is unknown. Immunosuppression may lower vaccine efficacy, so immunocompromised patients should adhere to recommended infection control practices. COVID-19 vaccination with Pfizer-BioNTech, Moderna, or Johnson & Johnson vaccines is safe for immunocompromised patients. |
| Databáze: | OpenAIRE |
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