A Novel Solvent-Free Approach to Imidazole Containing Nitrogen-Bridgehead Heterocycles
| Autor: | Fabio Mantellini, Gianfranco Favi, Orazio A. Attanasi, Luca Bianchi, Lucia De Crescentini, Linda A. Campisi |
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| Rok vydání: | 2013 |
| Předmět: |
Solvent free
Molecular Structure Pyridines Organic Chemistry Imidazoles chemistry.chemical_element Biochemistry Nitrogen Combinatorial chemistry chemistry.chemical_compound chemistry Cascade reaction Heterocyclic Compounds Simple (abstract algebra) Quinolines Solvents Molecule Imidazole Physical and Theoretical Chemistry |
| Zdroj: | Organic Letters. 15:3646-3649 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/ol4015267 |
| Popis: | A very simple domino reaction under solvent-free conditions of various pyridine-like heterocycles with 1,2-diaza-1,3-dienes produces in good yields imidazo[1,2-a]pyridines, imidazo[1,2-a]quinolines, and imidazo[2,1-a]isoquinolines. The advantage of this one-pot transformation lies in the use of simple pyridine-like compounds without prefunctionalization of the starting heterocycles. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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