The role of immunophenotyping in differential diagnosis of chronic lymphocytic leukemia
| Autor: | Andrija Bogdanovic, Nada Kraguljac-Kurtovic, Mirjana Gotic, Biljana Bozic, Tijana Dragovic-Ivancevic, Biljana Mihaljevic, Vesna Knezevic |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Chronic lymphocytic leukemia lcsh:Medicine Diagnosis Differential Immunophenotyping immunophenotyping Antigen Antigens CD Predictive Value of Tests immune system diseases hemic and lymphatic diseases Humans Medicine Lymphocyte Count Lymphocytes Aged Retrospective Studies Aged 80 and over CD20 biology business.industry flow cytometry lcsh:R CD23 General Medicine Middle Aged CD79B medicine.disease Leukemia Lymphocytic Chronic B-Cell Leukemia Immunology biology.protein chronic lymphocytic leukemia Female CD5 business |
| Zdroj: | Srpski Arhiv za Celokupno Lekarstvo, Vol 142, Iss 3-4, Pp 197-203 (2014) |
| ISSN: | 2406-0895 0370-8179 |
| DOI: | 10.2298/sarh1404197d |
| Popis: | Introduction. Accurate diagnosis of chronic lymphocytic leukemia (CLL) acquires immunophenotyping by flow cytometry in order to facilitate differential diagnosis between CLL and other mature B-cell neoplasms (MBCN). Objective. The aim of this study was to define immunological profile of CLL cells. Methods. Immunophenotyping by flow cytometry was performed on peripheral blood specimens at diagnosis in the group of 211 patients with de novo MBCN. Results. Absolute count of B-cells was significantly increased in all MBCN patients comparing to healthy control group (p |
| Databáze: | OpenAIRE |
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