Prions in dentistry: A need to be concerned and known
| Autor: | B Sushma, Sachin Gugwad, Shambhvi A Malik, Rajdeep Pavaskar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
animal diseases
Dentistry Disease Review Article Biology transmissible spongiform encephalopathies Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine mental disorders medicine Infection control 030212 general & internal medicine Prion protein General Dentistry Fatal familial insomnia business.industry 030206 dentistry Standard methods medicine.disease Virology Review article nervous system diseases Otorhinolaryngology prion protein Immunology Kuru Prion business |
| Zdroj: | Journal of Oral and Maxillofacial Pathology : JOMFP |
| ISSN: | 1998-393X 0973-029X |
| Popis: | Prion diseases were first discovered by Stanley B. Prusiner who defined prions as infectious, transmissible proteinaceous particles that lack nucleic acid and are composed exclusively of a modified isoform of the noninfectious cellular prion protein (PrPC). These are incurable neurodegenerative conditions affecting both animals and humans. They may be sporadic, infectious or inherited in origin. Human prion diseases include Creutzfeldt-Jakob desease (CJD), Gerstmann- Straussler-Scheinker disease, Kuru and Fatal familial insomnia. Prions resist the conventional sterilization procedures and hence the dentists must be aware of such diseases so as to opt standard methods of infection control and decontamination for such infectious agents. This review article divulge the dentists with a brief overview of the characteristics of prions, the risk of transmission and the implications for infection control in dentist. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|