Therapeutic Efficacy of Neurostimulation for Depression: Techniques, Current Modalities, and Future Challenges

Autor: Faiza Bukhari, Misbah Nazir, Hafsah Akhtar, Muhammad Nabeel Anwar, Adeeb Shahzad
Rok vydání: 2016
Předmět:
Zdroj: Neuroscience Bulletin. 32:115-126
ISSN: 1995-8218
1673-7067
DOI: 10.1007/s12264-015-0009-2
Popis: Depression is the most prevalent debilitating mental illness; it is characterized as a disorder of mood, cognitive function, and neurovegetative function. About one in ten individuals experience depression at some stage of their lives. Antidepressant drugs are used to reduce the symptoms but relapse occurs in ~20% of patients. However, alternate therapies like brain stimulation techniques have shown promising results in this regard. This review covers the brain stimulation techniques electroconvulsive therapy, transcranial direct current stimulation, repetitive transcranial magnetic stimulation, vagus nerve stimulation, and deep brain stimulation, which are used as alternatives to antidepressant drugs, and elucidates their research and clinical outcomes.
Databáze: OpenAIRE