Bleomycin-induced flagellate hyperpigmentation: Clinical Image
| Autor: | Bhusan Madke, Sumit Kar, Sushil Kumar Varma, Shanta Das Sutradhar |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment lcsh:Medicine chemotherapy Bleomycin Ovarian dysgerminoma chemistry.chemical_compound Medicine Flagellate Chemotherapy biology business.industry lcsh:R Low dose Bleomycin Sulfate lcsh:Other systems of medicine lcsh:RZ201-999 biology.organism_classification Dermatology Hyperpigmentation chemistry medicine.symptom business Complication flagellate hyperpigmentation |
| Zdroj: | Journal of Mahatma Gandhi Institute of Medical Sciences, Vol 19, Iss 1, Pp 72-73 (2014) |
| ISSN: | 0971-9903 |
| DOI: | 10.4103/0971-9903.126263 |
| Popis: | Flagellate hyperpigmentation is a unique complication of systemic bleomycin sulfate therapy. It has an onset anywhere between 1 day and several months after administration for various indications and these eruptions are usually dose-dependent. The dose of bleomycin required to produce such an effect is usually more than 100 U but it can also occur at lower doses also. Herewith, we describe a case with clinical image of ovarian dysgerminoma that presented with typical linear and streaked pigmentation following a very low dose (30 U) of systemic bleomycin therapy which appeared within 24 h of administration and increased gradually after subsequent doses. |
| Databáze: | OpenAIRE |
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