N-Funktionalisierungen an Sulfoximinen : N-Alkinylierte, N-Tetrafluorpyridylierte und N-Schwefel-funktionalisierte Sulfoximine
| Autor: | Fergen, Hannah |
|---|---|
| Přispěvatelé: | Bolm, Carsten, Albrecht, Markus |
| Jazyk: | němčina |
| Rok vydání: | 2022 |
| Předmět: |
Derivatisierung
Dithiocarbamate sulfoximine Sulfamate disulfiram Organische Chemie organic chemistry Schwefel sulfur Sulfoximine sulfoximine Funktionalisierung functionalization Derivatisierung derivatization Azomethin-Ylide azomethine ylide Dithiocarbamate dithiocarbamate Disulfiram disulfiram Pentafluorpyridin pentafluoropyridine Sulfamate sulfamate Organische Chemie Azomethin-Ylide Funktionalisierung organic chemistry pentafluoropyridine azomethine ylide sulfur ddc:540 derivatization functionalization Pentafluorpyridin Schwefel |
| Zdroj: | Aachen : RWTH Aachen University 1 Online-Ressource : Illustrationen, Diagramme (2022). doi:10.18154/RWTH-2022-09151 = Dissertation, RWTH Aachen University, 2022 |
| DOI: | 10.18154/rwth-2022-09151 |
| Popis: | Dissertation, RWTH Aachen University, 2022; Aachen : RWTH Aachen University 1 Online-Ressource : Illustrationen, Diagramme (2022). = Dissertation, RWTH Aachen University, 2022 Sulfur-containing functional groups are of great significance in the search for bioactive scaffolds, and among these, sulfoximines are attracting increasing attention. This work deals with the N-functionalizations of sulfoximines. In the first part, N-alkynylated sulfoximines are studied, investigating the synthesis of terminal N-alkynyl groups and the reactivity with azomethine ylides. The second part of the work describes the base-mediated production of N-tetrafluoropyridylated sulfoximines. In the third part, the focus is on N-sulfur functionalized sulfoximines. The regioselective synthesis and reactivity of sulfoximidyl-dithiocarbamates are studied. Furthermore, the preparation of sulfoximidyl-sulfamates via N-chlorosulfonyl and N-sulfonato-sulfoximines is described. Published by RWTH Aachen University, Aachen |
| Databáze: | OpenAIRE |
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