Newly diagnosed adult-onset Still's disease with pure red cell aplasia in pregnancy
| Autor: | Mahmoud Fathy Hassan, Mahmoud I. Moussa |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Pathology Fever Leukocytosis Prednisolone Anti-Inflammatory Agents Pure red cell aplasia Mean corpuscular hemoglobin Red-Cell Aplasia Pure Pregnancy medicine Humans Mean corpuscular volume Glucocorticoids medicine.diagnostic_test business.industry Obstetrics and Gynecology General Medicine medicine.disease Pregnancy Complications Treatment Outcome Pregnancy Trimester Second Etiology Gestation Female medicine.symptom business Still's Disease Adult-Onset medicine.drug |
| Zdroj: | Archives of gynecology and obstetrics. 290(1) |
| ISSN: | 1432-0711 |
| Popis: | Adult-onset Still’s disease (AOSD) is a rare inflammatory disease of unknown etiology that can present for the first time during pregnancy. Pure red cell aplasia (PRCA) is another rare condition that seldom is in association with AOSD. Herein, we have reported a newly diagnosed case with AOSD and PRCA in a previously healthy pregnant woman. A 25-year-old primigravida lady presented with fever, malaise, and arthralgia at 26 weeks of gestation. She had an extensive evaluation that led to the diagnosis of AOSD. Preliminary blood tests displayed a severe anemia with hemoglobin 5.1 g/dL, leukocytosis (total white blood cells count of 26,000 μL−1), normal mean corpuscular volume, normal mean corpuscular hemoglobin, normal platelet count, and a low reticulocyte count (0.2 %). The condition was diagnosed as AOSD associated with PRCA. She was treated with prednisolone and had immediate and dramatic improvement. AOSD and PRCA in pregnancy are rare conditions. The recognition of these clinical syndromes may lead to earlier diagnosis and thus prevent the expensive investigations. Both conditions have a dramatic improvement upon using corticosteroids therapy. |
| Databáze: | OpenAIRE |
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