DIAGNOSTIC AND PROGNOSTIC VALUE OF OSTEOPONTIN IN ACUTE CONGESTIVE HEART FAILURE -A PRELIMINARY STUDY
| Autor: | Florian Espeter, Michael Behnes, Parviz Ahmad-Nejad, Ursula Hoffmann, Siegfried Lang, Martin Borggrefe, Martina Brueckmann, Michael Neumaier |
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| Rok vydání: | 2012 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty biology business.industry medicine.disease Acute congestive heart failure Extracellular matrix Mediator stomatognathic system chemistry Fibrosis Internal medicine Heart failure medicine biology.protein Cardiology Osteopontin Glycoprotein business Cardiology and Cardiovascular Medicine Value (mathematics) |
| Zdroj: | Journal of the American College of Cardiology. 59(13) |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/s0735-1097(12)60951-6 |
| Popis: | Congestive heart failure is characterized by an adverse structural remodeling of the myocardium. Osteopontin is a glycoprotein being expressed in cardiomyocytes and fibroblasts. Osteopontin is involved in extracellular matrix formation and acts as a mediator of myocardial remodeling and fibrosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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