Hand pattern indicates prostate cancer risk
| Autor: | Amanda L. Hall, Jo-Fen Liu, Elizabeth Page, Douglas F. Easton, Terence L. Parker, David P. Dearnaley, Kenneth Muir, Richard Pocock, Rosemary A. Wilkinson, Michelle Guy, John Anderson, Lynne T. O'Brien, Aneela Atta Ur Rahman, Zsofia Kote-Jarai, D. Harriss, Artitaya Lophatananon, Rosalind A. Eeles, Sarah Stewart-Brown, Elinor Sawyer |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Short Communication hand pattern Population Urology Lower risk Fingers Prostate cancer Risk Factors medicine Ring finger Humans education Letter to the Editor Aged Aged 80 and over Gynecology education.field_of_study business.industry Case-control study Prostatic Neoplasms case–control study Index finger Odds ratio Middle Aged prostate cancer Hand medicine.disease Confidence interval medicine.anatomical_structure Oncology Case-Control Studies business |
| Zdroj: | British Journal of Cancer |
| ISSN: | 1532-1827 0007-0920 |
| DOI: | 10.1038/sj.bjc.6605986 |
| Popis: | Background: The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels. Methods: We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls. Results: Compared with index finger shorter than ring finger (low 2D : 4D), men with index finger longer than ring finger (high 2D : 4D) showed a negative association, suggesting a protective effect with a 33% risk reduction (odds ratio (OR) 0.67, 95% confidence interval (CI) 0.57–0.80). Risk reduction was even greater (87%) in age group |
| Databáze: | OpenAIRE |
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