Clinical study to monitor dentinal hypersensitivity with episodic use of a desensitising dentifrice
Autor: | Lucy Shneyer, Rose Kingston, Stephen Mason, Mairead Harding |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
business.industry
Dentine hypersensitivity Calcium/Sodium Tactile threshold Dentistry 030206 dentistry Article Clinical study 03 medical and health sciences 0302 clinical medicine Fluoride dentifrice Tooth Sensitivity Dentifrice Medicine 030212 general & internal medicine business Adverse effect General Dentistry |
Zdroj: | BDJ Open |
ISSN: | 2056-807X |
Popis: | Objectives/Aims: To evaluate continuous and episodic twice-daily usage regimens of a desensitising dentifrice containing 5% calcium sodium phosphosilicate (CSPS). Materials and Methods: In this exploratory, single-centre, randomised, examiner-blind study, subjects with dentinal hypersensitivity were randomised to continuous (24 weeks) use of a 5% CSPS-containing dentifrice or episodic use of the dentifrice comprising two 8-week treatment periods separated by 8 weeks′ use of a standard fluoride dentifrice. Sensitivity was assessed by tactile threshold (Yeaple probe) and evaporative (air) sensitivity (Schiff sensitivity score). Other measures included labelled magnitude scales to assess subjects′ responses to the evaporative stimulus, the Dentine Hypersensitivity Experience Questionnaire and a tooth sensitivity question. Results: Seventy-six subjects were randomised to continuous (n=38) or episodic (n=38) use. Small but statistically significant improvements from baseline in Schiff sensitivity scores were observed at weeks 8, 16 and 24 with both regimens (all P Discussion: Dentifrice containing 5% CSPS improved dentinal hypersensitivity with both episodic and continuous twice-daily usage regimens over 24 weeks and was well tolerated. Conclusion: No performance differences were observed between the two usage regimens. |
Databáze: | OpenAIRE |
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