Lyophilized platelets versus cryopreserved platelets for management of bleeding in thrombocytopenic dogs: A multicenter randomized clinical trial

Autor:	Janine Calabro, Brenda Fulcher, John P. Loftus, Karyn Harrell, Anne S Hale, Teresa Lightfoot, April E Blong, Meredith L. Miller, Dana N. LeVine, Ashley Ziegler, Robert Goggs, John Gicking, Benjamin M. Brainard, Jennifer C. Kishbaugh, Tracy Mills, Benjamin L. Davidson, Christine Iacovetta, Richard Stone, Lauren Harris, Rebecca A. Walton, Mary Aslanian
Rok vydání:	2020
Předmět:	Blood Platelets 040301 veterinary sciences canine Hemorrhage Platelet Transfusion Standard Article 030204 cardiovascular system & hematology Hematocrit Cryopreservation law.invention 0403 veterinary science 03 medical and health sciences Dogs 0302 clinical medicine Platelet product Randomized controlled trial law medicine Animals Platelet Dog Diseases Adverse effect trehalose transfusion General Veterinary medicine.diagnostic_test Platelet Count business.industry Hematology 04 agricultural and veterinary sciences Thrombocytopenia Standard Articles Clinical trial Red blood cell medicine.anatomical_structure immune thrombocytopenia Anesthesia SMALL ANIMAL business
Zdroj:	Journal of Veterinary Internal Medicine
ISSN:	1939-1676 0891-6640
DOI:	10.1111/jvim.15922
Popis:	Background Thrombocytopenia in dogs is common in critical care medicine, but availability of fresh platelet concentrates in veterinary medicine can be limiting. Lyophilized platelets have long shelf‐lives and can be easily transported, stored, and administered in various settings. Objective To evaluate the efficacy and safety of a novel trehalose‐stabilized canine lyophilized platelet product in thrombocytopenic dogs with clinically‐evident bleeding. Animals Eighty‐eight dogs with platelet counts
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e839c0a5901e96c351705c54cb932bc9 https://doi.org/10.1111/jvim.15922 Zobrazit plný text záznamu Plný text