Bimatoprost 0.01% vs bimatoprost 0.03%: a 12-month prospective trial of clinical and in vivo confocal microscopy in glaucoma patients
| Autor: | Paolo Piaggi, Marco Nardi, M Sartini, Gianluca Guidi, Luca Martini, Stefano Lazzeri, Michele Figus |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
In vivo confocal microscopy Visual Acuity Glaucoma law.invention Ophthalmic pathology Neuro-ophthalmology Randomized controlled trial Blurred vision law Ophthalmology Eye Pain Humans Medicine Prospective Studies Prospective cohort study Antihypertensive Agents Intraocular Pressure Analysis of Variance Microscopy Confocal Bimatoprost business.industry Repeated measures design Cloprostenol Middle Aged medicine.disease Amides eye diseases Prospective trial Tears Clinical Study medicine.symptom Corrigendum business medicine.drug |
| Zdroj: | Eye. 28:422-429 |
| ISSN: | 1476-5454 0950-222X |
| DOI: | 10.1038/eye.2013.304 |
| Popis: | To evaluate the safety of two commercially available formulations of bimatoprost eye drops: 0.03 and 0.01% ophthalmic solutions. This was a randomized, prospective, parallel-group, open-label, cohort study. A total of 60 glaucoma patients (60 eyes) under bimatoprost 0.03% monotherapy since at least 1 year were enrolled. Selected patients were randomized to receive a single drop of bimatoprost 0.01% (n=30) or bimatoprost 0.03% (n=30) ophthalmic solutions for 12 months. Statistical analysis was performed using paired t-test and repeated measures ANOVA test. Global clinical score (the sum of pruritus, stinging/burning, blurred vision, sticky eye sensation, eye dryness sensation, and foreign body sensation) significantly decreased in the bimatoprost 0.01% group from baseline 4.7±3.8 to 2.9±2.3 (P |
| Databáze: | OpenAIRE |
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