Nutritional composition, antioxidant activity and anticancer potential of Syzygium cumini (L.) and Syzygium malaccense (L.) fruits
| Autor: | Luciana Gibbert, Aiane Benevide Sereno, Obdulio Gomes Miguel, Marilis Dallarmi Miguel, Michelli Aparecida Bertolazo da Silva, Deise Prehs Montrucchio, Aline Macedo Dantas, Josiane de Fátima Gaspari Dias, Marina Talamini Piltz de Andrade, Iara Messias-Reason, Claudia Carneiro Hecke Krüger, Graciele da Silva Campelo Borges |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Antioxidant
030309 nutrition & dietetics DPPH medicine.medical_treatment Nutritional composition Syzygium Antioxidante natural Nutracéuticos Natural antioxidant Terapia complementar 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology Nutraceutical medicine Viability assay Rim embrionário humano Câncer de pulmão General Environmental Science Complementary therapy 0303 health sciences Human embryonic kidney biology Traditional medicine Cell growth Chemistry Terapia complementaria Nutracêuticos 04 agricultural and veterinary sciences Riñón embrionario humano biology.organism_classification 040401 food science Cancer cell General Earth and Planetary Sciences Nutraceuticals Lung cancer Cancer de pulmon |
| Zdroj: | Research, Society and Development; Vol. 10 No. 4; e5210413743 Research, Society and Development; Vol. 10 Núm. 4; e5210413743 Research, Society and Development; v. 10 n. 4; e5210413743 Research, Society and Development Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
| ISSN: | 2525-3409 |
| Popis: | Intending to highlight new fruits with nutraceutical potential, the present work reports the nutritional and antioxidant content of Syzygium cumini (L.) Skeels (S. cumini) and Syzygium malaccense (L.) Merr. & LM Perry (S. malaccense), and evaluates the anticancer potential against CP-H460 (lung carcinoma line) and its functionality over HEK-293 (healthy embryonic kidney line), two human cells. For this, the physical-chemical characterization of the lyophilized fruits was carried out, and the content of total phenolic compounds (Folin-Ciocalteau) and the antioxidant potential (DPPH, FRAP, and ORAC) was determined. For anticancer activity, aqueous extracts were prepared and evaluated using the MTT (3-[4,5-dimethyl-triazol-2-yl]-2,5-diphenyltetrazolium) assay for periods of 20 hours. These two species are rich in dietary fibers, mainly insoluble fibers, and are sources of natural compounds and antioxidants, which possibly explain the protective potential against cancer cells. Thus, it is expected, as two source fruits, results obtained (p |
| Databáze: | OpenAIRE |
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