ASSOCIATION BETWEEN CHOROIDAL CAVERNS AND CHOROIDAL VASCULAR HYPERPERMEABILITY IN EYES WITH PACHYCHOROID DISEASES
| Autor: | K. Bailey Freund, Yoichi Sakurada, Belinda C S Leong, Ravi Parikh, Serena Fragiotta |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Indocyanine Green Male retina medicine.medical_specialty genetic structures Indocyanine green angiography 03 medical and health sciences 0302 clinical medicine Ophthalmology 0502 economics and business medicine Humans Fluorescein Angiography Aged Retrospective Studies Retrospective review Choroid business.industry 05 social sciences choriod Choroid Diseases General Medicine Middle Aged Pachycaverns Choroidal Neovascularization pachychoroid eye diseases Serous fluid Central Serous Chorioretinopathy 030221 ophthalmology & optometry Female 050211 marketing sense organs business Tomography Optical Coherence |
| Zdroj: | Retina. 38:1977-1983 |
| ISSN: | 0275-004X |
| Popis: | PURPOSE To investigate the association between choroidal caverns, choroidal vascular hyperpermeability (CVH), and pachyvessels in eyes with pachychoroid disease. METHODS This was a retrospective review of swept-source optical coherence tomography and indocyanine green angiography imaging performed on eyes with pachychoroid disease. RESULTS Imaging from 21 eyes with pachychoroid disease entities (8 eyes with pachychoroid pigment epitheliopathy, 11 eyes with central serous chorioretinopathy, and 3 eyes with pachychoroid neovasculopathy) from 11 patients (mean 49.5 years, male/female: 10/1, all white) was available for review. In all study eyes, pachyvessels traversed the areas of CVH visible in mid- and late-phase indocyanine green angiography. A total of 504 choroidal caverns were identified in 11 study eyes (52%). Of the 504 choroidal caverns, 445 (88%) were seen within the areas of CVH compared with 59 (12%), which were detected outside the areas of CVH (P < 0.001). Eyes with multiple caverns had an increased choroidal thickness when compared with eyes with ≤1 cavern (P < 0.001). CONCLUSION Choroidal caverns, found primarily in the areas of indocyanine green angiography CVH traversed by pachyvessels, were detected in 52% of eyes with pachychoroid disease. The presence of choroidal caverns in these cases may indicate a loss of normal choroidal architecture associated with dilated Haller layer veins and increased choroidal thickness. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|