High-level mupirocin resistance in Gram-positive bacteria isolated from diseased companion animals
| Autor: | Hee Myung Park, Samuth Sum, Jae Young Oh |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
ANTIMICROBIAL SUSCEPTIBILITY TESTS
040301 veterinary sciences Staphylococcus Gram-positive bacteria Diseased pets Corynebacterium spread Microbial Sensitivity Tests Cat Diseases Polymerase Chain Reaction Microbiology 0403 veterinary science 03 medical and health sciences Dogs Drug Resistance Bacterial Internal Medicine Animals Dog Diseases Gene Polymerase staphylococci 030304 developmental biology 0303 health sciences Corynebacterium Infections General Veterinary biology mupA-IS257 Sequence Analysis DNA 04 agricultural and veterinary sciences Staphylococcal Infections biology.organism_classification Anti-Bacterial Agents Mupirocin resistance Mupirocin high-level mupirocin resistance Cats biology.protein lipids (amino acids peptides and proteins) Rapid Communication Bacteria |
| Zdroj: | Journal of Veterinary Science |
| ISSN: | 1976-555X 1229-845X |
| DOI: | 10.4142/jvs.2020.21.e40 |
| Popis: | The purpose of this study was to investigate the high-level mupirocin resistance (HLMR) in Gram-positive bacteria isolated from companion animals. A total of 931 clinical specimens were collected from diseased pets. The detection of mupirocin-resistant bacteria and plasmid-mediated mupirocin resistance genes were evaluated by antimicrobial susceptibility tests, polymerase chain reactions, and sequencing analysis. Four-hundred and six (43.6%) bacteria were isolated and 17 (4.2%), including 14 staphylococci and 3 Corynebacterium were high-level mupirocin-resistant (MICs, ≥ 1,024 ug/mL) harboring mupA. Six staphylococci of HLMR strains had plasmid-mediated mupA-IS257 flanking regions. The results show that HLMR bacteria could spread in veterinary medicine in the near future. |
| Databáze: | OpenAIRE |
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