Histopathologic spectrum of childhood tumours in a Tertiary Hospital: a ten-year review
| Autor: | Adewumi B. Oyesakin, Said Amin, Emmanuel A. Ameh, Abdurasaq R Oyesegun, V. E. Nwatah |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Lymphoma 030231 tropical medicine Nigeria haemangioma Benign tumours spectrum Tertiary Care Centers 03 medical and health sciences Age Distribution 0302 clinical medicine Neoplasms Prevalence medicine Vascular Neoplasm Humans Neoplasm Registries Sex Distribution Child Retrospective Studies Childhood tumours Germ cell neoplasm business.industry Infant Newborn Infant Articles General Medicine medicine.disease Neural Neoplasm Child Preschool Cohort Female Histopathology Hemangioma business |
| Zdroj: | African Health Sciences |
| ISSN: | 1680-6905 |
| DOI: | 10.4314/ahs.v21i1.9 |
| Popis: | Background: There has been a growing public health burden of childhood tumours in low and middle income countries (LMICs) as the trend in epidemiological transition continues to vary. Objective: The objective of this report is to determine the spectrum of childhood tumours at a tertiary hospital in Nigeria. Methods: A retrospective review of the histopathology register over the period January 2006 to December 2015. Results: The total paediatric tumour cases was 248, including 143 (57.7%) females and 105 (42.3%) males, aged 0 – 12 years (mean 6.1years ± 3.97 SD). The age group 2 - 5 year cohort had the highest prevalence of tumour. The predominant tumour based on tissue of origin was epithelial neoplasms 88 (35.5%), vascular neoplasms 56 (22.6%), neural neoplasm 42 (16.9%), mesenchymal neoplasm 37 (14.9%), germ cell neoplasm 13 (5.2%) and haematopoietic neoplasms 12 (4.8%). Majority of the tumours were benign, 148 (59.7%) and malignant 100 (40.3%). The most predominant benign tumour was haemangioma 33 (13.3%) and predominant malignant tumour was lymphoma 22 (8.9%). Conclusion: Benign tumours remain the commonest neoplasm of children in this hospital-based data. Development and implementation of a tumour registry would provide a more comprehensive information. Keywords: Childhood tumours; spectrum; haemangioma; lymphoma. |
| Databáze: | OpenAIRE |
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