Comparing a high-dose dipyridamole SPECT imaging protocol with dobutamine and exercise stress testing protocols. Part III: Using dobutamine to determine lung-to-heart ratios, left ventricular dysfunction, and a potential viability marker
| Autor: | Diane M. Fleming, Richard M. Fleming, Kristine M. Feldmann |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry chemistry.chemical_element Single-photon emission computed tomography medicine.disease Coronary artery disease Dipyridamole Coronary arteries medicine.anatomical_structure chemistry Spect imaging Internal medicine medicine Cardiology Thallium Dobutamine Cardiology and Cardiovascular Medicine business medicine.drug Angiology |
| Zdroj: | International Journal of Angiology. 8:22-26 |
| ISSN: | 1615-5939 1061-1711 |
| Popis: | Determination of the severity of coronary artery disease (CAD) by single photon emission computed tomography (SPECT) imaging has previously been shown to have greater sensitivity, specificity, and accuracy when performed with pharmacologic stress using dobutamine than by standard dose dipyridamole (SDD) or exercise stress testing (EST) prior to SPECT imaging. The use of lung to heart (L:H) ratios has been shown to be valuable in determining the presence or absence of left main (LM) or triple vessel (3V) CAD. No such work has been previously reported for dobutamine. Twenty-one patients were studied using dobutamine (n = 7) or EST (n = 14). These results were compared with results from Part II of this series of studies using high-dose dipyridamole (HDD) pharmacologic stress. In this study, patients underwent L:H ratio analysis following injection of 3 mCi of Tl-201, this provides sufficient time for thallium clearance from the blood pool. Results of the L:H ratios were compared with the results of coronary arteriographic (CA) evaluation. Patients who were "stressed" via EST demonstrated statistically greater (p |
| Databáze: | OpenAIRE |
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