The Artificial Kidney and Ion-Exchange Resins as Possible Methods of Removing Radioelements from the Body

Autor: C. J. Maletskos, John Reardon, Warren Guild, Marie Helmick, W. B. Looney, J. Cohen
Rok vydání: 1957
Předmět:
Zdroj: Radiology. 68:255-256
ISSN: 1527-1315
0033-8419
Popis: The classic studies of Aub, Evans et al. (1) in 1938 in radioelement removal demonstrated that the renal clearance for radium was less than 1 per cent in twenty-four hours. This finding suggested the possibility that direct radioelement removal from the blood might prove to be an effective way of eliminating radioelements. Both the artificial kidney (2) and ion-exchange resins (3) afford means for radioelement removal, as well as providing an opportunity for extension of the work by Hastings and Huggins (4) on the mobilization of calcium in the circulating body fluids. Preliminary in vitro experiments were performed to determine some of the parameters necessary to evaluate the feasibility of using either approach. The first experiments were carried out on a simulated artificial kidney. Stable calcium, calcium 45, and ethylenediaminetetraacetic acid were readily dialyzable under conditions similar to those in the artificial kidney (calcium being omitted for the purpose of the present experiments) (5). In l...
Databáze: OpenAIRE