The Artificial Kidney and Ion-Exchange Resins as Possible Methods of Removing Radioelements from the Body
Autor: | C. J. Maletskos, John Reardon, Warren Guild, Marie Helmick, W. B. Looney, J. Cohen |
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Rok vydání: | 1957 |
Předmět: |
medicine.medical_specialty
business.industry Calcium Radioisotopes Radiochemistry chemistry.chemical_element Ethylenediaminetetraacetic acid Calcium Artificial kidney Surgery Radium chemistry.chemical_compound chemistry Strontium Strontium Radioisotopes Medicine Radiology Nuclear Medicine and imaging Ion Exchange Resins Calcium-45 business Ion-exchange resin Kidneys Artificial Clearance |
Zdroj: | Radiology. 68:255-256 |
ISSN: | 1527-1315 0033-8419 |
Popis: | The classic studies of Aub, Evans et al. (1) in 1938 in radioelement removal demonstrated that the renal clearance for radium was less than 1 per cent in twenty-four hours. This finding suggested the possibility that direct radioelement removal from the blood might prove to be an effective way of eliminating radioelements. Both the artificial kidney (2) and ion-exchange resins (3) afford means for radioelement removal, as well as providing an opportunity for extension of the work by Hastings and Huggins (4) on the mobilization of calcium in the circulating body fluids. Preliminary in vitro experiments were performed to determine some of the parameters necessary to evaluate the feasibility of using either approach. The first experiments were carried out on a simulated artificial kidney. Stable calcium, calcium 45, and ethylenediaminetetraacetic acid were readily dialyzable under conditions similar to those in the artificial kidney (calcium being omitted for the purpose of the present experiments) (5). In l... |
Databáze: | OpenAIRE |
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