Integral Indicator of Oxidative Stress in Human Blood
| Autor: | M. A. Darenskaya, L. I. Kolesnikova, L. V. Suturina, N. V. Semyonova, S. V. Gnusina, Lyudmila Grebenkina |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Infertility medicine.medical_specialty alpha-Tocopherol Conjugated system medicine.disease_cause Thiobarbituric Acid Reactive Substances Antioxidants Statistics Nonparametric General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Internal medicine Diabetes mellitus medicine Humans Vitamin A Type 1 diabetes Human blood Superoxide Dismutase Retinol General Medicine medicine.disease Glutathione Hyperprolactinemia Oxidative Stress Diabetes Mellitus Type 1 Endocrinology chemistry Endocrine pathology Female Lipid Peroxidation Infertility Female Biomarkers Oxidative stress |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 157:715-717 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-014-2649-z |
| Popis: | Here we performed individual evaluation of the oxidative stress index that serves as an integral criterion for the balance of LPO-antioxidant defense system in women with endocrine pathology (type 1 diabetes mellitus and infertility with hyperprolactinemia). The state of the LPO-antioxidant defense system was estimated from blood levels of LPO substrates with conjugated double bonds, conjugated dienes, ketodienes, conjugated trienes, thiobarbituric acid-reactive substances, retinol, α-tocopherol, reduced and oxidized glutathione, and SOD activity. The use of this oxidative stress index allowed us to diagnose oxidative stress in female patients with endocrine pathology. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink