Factors Associated With Diastolic Dysfunction in Patients With Resistant Hypertension: Resist-POL Study
| Autor: | Paweł Śliwiński, Piotr Hoffman, Piotr Dobrowolski, Przemyslaw Bielen, Aleksander Prejbisz, Maria Gosk, Justyna Rybicka, Anna Klisiewicz, Andrzej Januszewicz, Elżbieta Florczak |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Ambulatory blood pressure Heart Ventricles Diastole Blood Pressure Polysomnography Ventricular Dysfunction Left Young Adult Internal medicine Internal Medicine medicine Humans Abdominal obesity Aged Metabolic Syndrome Sleep Apnea Obstructive medicine.diagnostic_test business.industry Age Factors Middle Aged medicine.disease Obstructive sleep apnea Blood pressure Echocardiography Hypertension Cardiology Female Metabolic syndrome medicine.symptom business Hypopnea |
| Zdroj: | American Journal of Hypertension. 28:307-311 |
| ISSN: | 1941-7225 0895-7061 |
| Popis: | background Diastolic dysfunction has been shown to be an independent factor of cardiovascular diseases in patients with hypertension. Very often, obstructive sleep apnea (OSA) and metabolic syndrome (MS) coexist with resistant hypertension (RHTN) and may lead to diastolic dysfunction. Thus, the purpose of this study was to investigate whether OSA and MS are associated with diastolic dysfunction in patients with RHTN independently from other factors, including age, left ventricular mass index (LVMI), and blood pressure (BP). methods Data from 155 patients (n = 92 men and 63 women) were analyzed. All patients underwent thorough examination, including biochemical evaluations, ambulatory blood pressure monitoring, polysomnography with assessment of apnea/hypopnea index (AHI), and echocardiography. LVMI and diastolic function parameters were obtained. results Patients were divided into 2 groups based on the presence or absence of diastolic dysfunction: group 1 (E’ 10 cm/second; n = 68). AHI, LVMI, and 24-hour systolic BP/diastolic BP values were higher in group 1. E’ correlated with AHI (r = −0.25; P < 0.001), LVMI (r = −0.36; P < 0.0001), 24-h systolic BP/24-h diastolic BP (r = −0.28, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|