Cognition and mortality from the major causes of death: the Health and Lifestyle Survey
| Autor: | Michelle D. Taylor, Ian J. Deary, Beverly A. Shipley, Geoff Der |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Gerontology
Adult Male Risk medicine.medical_specialty Lung Neoplasms Adolescent Psychometrics Respiratory Tract Diseases Disease Neuropsychological Tests Young Adult Cause of Death medicine Reaction Time Health Status Indicators Humans Effects of sleep deprivation on cognitive performance Stroke Life Style Problem Solving Aged Aged 80 and over business.industry Public health Hazard ratio Cognition Middle Aged medicine.disease Health Surveys United Kingdom Cognitive test Psychiatry and Mental health Clinical Psychology Memory Short-Term Cardiovascular Diseases Female business Cognition Disorders Body mass index Psychomotor Performance |
| Zdroj: | Journal of psychosomatic research. 65(2) |
| ISSN: | 0022-3999 |
| Popis: | Objective To investigate the influence of reaction time and cognition on the risk of death from cause-specific mortality and to examine whether any association found remains after adjustment for available socioeconomic, lifestyle, and health factors. Methods Participants were from the UK Health and Lifestyle Survey. The sample consisted of 6424 community dwelling individuals aged between 18 and 97 years at baseline (1984/1985). Sociodemographic, lifestyle, health, and physiological information was collected alongside cognitive testing which included simple (SRT) and choice (CRT) reaction time, a short-term memory test, and a test of visual–spatial reasoning. Participants have been followed for 21 years for cause-specific mortality. Results Slower and more variable reaction times and poorer cognitive performance were associated with a higher risk of death from cardiovascular disease, stroke, and respiratory disease after controlling for age and sex. Slight attenuation was noted after adjustments for all covariates. However, only CRT mean remained significantly associated with death from respiratory disease. No associations were found for coronary heart disease, lung cancer, and all nonlung cancers. Significant cognition–mortality associations were mostly obtained in those aged over 60 years. The possibility of reverse causality was partly excluded by reanalysing the data after omitting individuals who died within 5 years of cognitive testing. Conclusions Slower and more variable reaction times and poorer cognitive performance were related to an increased risk of mortality from cardiovascular disease, stroke, and respiratory disease. The possibility of reverse causality requires further testing. |
| Databáze: | OpenAIRE |
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