Treatment of Metabolic Alkalosis during Continuous Renal Replacement Therapy with Regional Citrate Anticoagulation
| Autor: | J Amman, Stanislao Morgera, Detlef Kindgen-Milles, Wolfgang Kleinekofort |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.drug_class medicine.medical_treatment 030232 urology & nephrology Biomedical Engineering Metabolic alkalosis Medicine (miscellaneous) Bioengineering 030204 cardiovascular system & hematology Systemic circulation Extracorporeal Biomaterials 03 medical and health sciences 0302 clinical medicine Renal Dialysis medicine Humans Citrate anticoagulation Citrates Renal replacement therapy Aged Acid-Base Equilibrium business.industry Anticoagulant Life time Anticoagulants Alkalosis General Medicine Acute Kidney Injury Hydrogen-Ion Concentration medicine.disease Hemodialysis Solutions Surgery Bicarbonates Liver Regional Blood Flow Anesthesia Hemodialysis business |
| Zdroj: | The International Journal of Artificial Organs. 31:363-366 |
| ISSN: | 1724-6040 0391-3988 |
| DOI: | 10.1177/039139880803100414 |
| Popis: | The use of citrate as an anticoagulant in continuous renal replacement therapy is an effective method to achieve regional anticoagulation of the extracorporeal blood circuit and to avoid systemic anticoagulation. This allows bleeding complications to be reduced and filter life time to be prolonged. However, citrate enters the systemic circulation and is metabolized in the liver to bicarbonate, causing metabolic alkalosis in some patients. In this case report, we discuss therapeutic interventions to control the acid-base status and to restore normal pH during continuous citrate hemodialysis. |
| Databáze: | OpenAIRE |
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