Iron Polymaltose Infusion Effects on Bone Scintigraphy and Remodeling

Autor:	Christine, Kang, James Y, Jiang, Veronica, Wong, Jennifer, Man, Robert, Mansberg
Rok vydání:	2022
Předmět:	Humans Bone Neoplasms Breast Neoplasms Female Radiology Nuclear Medicine and imaging General Medicine Radionuclide Imaging Tomography X-Ray Computed Ferric Compounds Aged
Zdroj:	Clinical Nuclear Medicine. 47:e627-e629
ISSN:	1536-0229 0363-9762
DOI:	10.1097/rlu.0000000000004171
Popis:	A 73-year-old woman with metastatic breast cancer and known widespread skeletal metastases was referred for bone scintigraphy. Delayed images acquired at 2 and 5 hours postinjection of 30 mCi (1089 MBq) 99mTc-HDP demonstrated markedly reduced bony uptake, markedly increased renal activity, and significantly increased soft tissue accumulation. By contrast, appropriate skeletal uptake of 99mTc-HDP was seen in prior bone scans. The patient had been treated for iron deficiency anemia with an infusion of 1 g of iron polymaltose approximately 22 hours before injection of 99mTc-HDP. This phenomenon may be due to transient reduced bone resorption with increased FGF23 release secondary to IV iron supplementation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e7e54b53098e198d3e025f50d0596e https://doi.org/10.1097/rlu.0000000000004171 Zobrazit plný text záznamu