Dysnatremia in extremely low birth weight infants is associated with multiple adverse outcomes
| Autor: | Christine Nicole Aune, James Aden, Nicholas Carr, Kaashif A. Ahmad, Thornton S. Mu, William Lefkowitz, Christopher S Monnikendam |
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| Rok vydání: | 2018 |
| Předmět: |
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Pediatrics medicine.medical_specialty Databases Factual Sodium chemistry.chemical_element 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Intensive care Intensive Care Units Neonatal medicine Humans 030212 general & internal medicine Retrospective Studies Hypernatremia business.industry Case-control study Infant Newborn Obstetrics and Gynecology Retrospective cohort study medicine.disease Low birth weight chemistry Infant Extremely Low Birth Weight Case-Control Studies Infant Extremely Premature Pediatrics Perinatology and Child Health Cohort Female medicine.symptom business Hyponatremia |
| Zdroj: | Journal of perinatology : official journal of the California Perinatal Association. 39(6) |
| ISSN: | 1476-5543 |
| Popis: | OBJECTIVE The objective of this study is to discern patterns of serum sodium in a broad cohort of extremely low birth weight (ELBW) infants and associate those patterns with hospital outcomes. STUDY DESIGN Retrospective cohort study of ELBW infants from 323 neonatal intensive care units (NICUs) discharged from 2004 to 2014. We included patients who survived at least 7 days and had daily sodium levels available, and categorized infants by their minimum and maximum sodium levels. RESULTS We identified 26,871 infants of whom 12,428 met inclusion criteria. Only 1964 (15.8%) maintained eunatremia for the first week. We found most dysnatremias to be associated with increased overall mortality compared with eunatremic patients including moderate hyponatremia (12.9% vs. 8.6%, p |
| Databáze: | OpenAIRE |
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