Thyrotoxic dilated cardiomyopathy: personal experience and case collection from the literature
| Autor: | Elio Badolati, Giuseppina Molinaro, Raffaele Giannattasio, Renato De Vecchis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty endocrine system endocrine system diseases Endocrinology Diabetes and Metabolism medicine.medical_treatment December Cardiology 030209 endocrinology & metabolism White lcsh:Diseases of the endocrine glands. Clinical endocrinology 03 medical and health sciences 0302 clinical medicine Internal medicine Internal Medicine medicine Extracorporeal membrane oxygenation Thyroid lcsh:RC648-665 business.industry Cardiogenic shock Dilated cardiomyopathy medicine.disease Unique/Unexpected Symptoms or Presentations of a Disease medicine.anatomical_structure Blood pressure Carbimazole Italy 030220 oncology & carcinogenesis Heart failure Propylthiouracil business hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2021) Endocrinology, Diabetes & Metabolism Case Reports |
| ISSN: | 2052-0573 |
| Popis: | Summary The authors examine several reports of the literature concerning thyrotoxic dilated cardiomyopathy. In particular, it is pointed out that this clinical manifestation of hyperthyroidism is rare in readily diagnosed and properly treated hyperthyroidism. Case reports are analyzed comparatively. A case deriving from the direct experience of the authors is also presented. Learning points: Dilated cardiomyopathy has been reported as the initial presentation of hyperthyroidism in only 6% of patients although Clinical picture of thyrotoxic dilated cardiomyopathy can degenerate into an overt cardiogenic shock sometimes requiring the use of devices for mechanical assistance to the circulation, or extracorporeal membrane oxygenation. For thyrotoxic dilated cardiomyopathy, evidence-based pharmacologic measures valid for heart failure should always be supplemented by the administration of specific thyroid therapies such as thionamides (methimazole, carbimazole or propylthiouracil), whose relatively long latency of action should be supported by the i.v. administration of small doses of beta-blocker. In cases of cardiogenic shock, the administration of beta-blocker should be carried out only after the restoration of satisfactory blood pressure levels- with the prudent use of synthetic catecholamines, if necessary. |
| Databáze: | OpenAIRE |
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