Impact of the outcome of fresh blastocyst transfer on the subsequent frozen-thawed blastocyst transfer cycle
| Autor: | Tarek El-Toukhy, Omar El Tokhy, Jyotsna Pundir, Yacoub Khalaf, Yusuf Beebeejaun, Julia Kopeika |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Adult Pregnancy Rate Biology Endometrium Cryopreservation Andrology 03 medical and health sciences 0302 clinical medicine Embryo cryopreservation Pregnancy Freezing medicine Positive Pregnancy Test Humans Survival rate reproductive and urinary physiology 030219 obstetrics & reproductive medicine Blastocyst Transfer Obstetrics and Gynecology medicine.disease Embryo Transfer 030104 developmental biology medicine.anatomical_structure Reproductive Medicine embryonic structures Female Live birth Live Birth Developmental Biology |
| Zdroj: | Reproductive biomedicine online. 35(5) |
| ISSN: | 1472-6491 |
| Popis: | The objective of this observational study was to assess the influence of the outcome of fresh blastocyst transfer on the success rate of the subsequent sibling frozen-thawed blastocyst transfer (FBT) cycle. In total, 1639 FBT cycles were divided into two groups: Group A (n = 698) cycles in which a positive pregnancy test result was achieved and Group B (n = 941) cycles in which no pregnancy was achieved in the preceding fresh IVF cycle. Mean age at cryopreservation, basal FSH level, number of oocytes retrieved, number of embryos transferred in the fresh cycle and survival rate of the thawed blastocysts in the FBT cycle were comparable between the two groups. Although significantly more thawed blastocysts were transferred in the FBT cycles in Group B compared with Group A, the live birth rate in Group A was significantly higher compared with Group B. After adjusting for potentially confounding variables, the likelihood of a live birth after FBT was significantly higher when a pregnancy was achieved in the preceding fresh IVF cycle. Achieving a pregnancy after fresh blastocyst transfer is an independent factor influencing the outcome of the subsequent sibling FBT. |
| Databáze: | OpenAIRE |
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