Individual Housing Modulates Daily Rhythms of Hypothalamic Catecholaminergic System and Circulating Hormones in Adult Male Rats
| Autor: | Di Renzo G, Sticchi R, Bellotti R, Gambardella P, Anna Maria Greco |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty Epinephrine Physiology Dopamine Metabolite Hypothalamus Biology Methoxyhydroxyphenylglycol Norepinephrine chemistry.chemical_compound Catecholamines Corticosterone Physiology (medical) Internal medicine medicine Animals Circadian rhythm Rats Wistar Catecholaminergic Dopaminergic Homovanillic Acid Hormones Prolactin Circadian Rhythm Rats Endocrinology Social Isolation chemistry 3 4-Dihydroxyphenylacetic Acid Stress Psychological Hormone medicine.drug |
| Zdroj: | Chronobiology International. 11:213-221 |
| ISSN: | 1525-6073 0742-0528 |
| DOI: | 10.3109/07420529409067790 |
| Popis: | Circadian rhythms of hypothalamic catecholamines and their metabolites and of prolactin and corticosterone circulating hormones were determined over 24 h in group-housed (six per cage; control) and individually housed, 90-day-old male albino rats adapted to a 12:12 light/dark cycle. After 5 weeks of adaptation, in individually housed rats, norepinephrine (NE) turnover increased, since lower NE (p < 0.01) and higher MOPEG metabolite (p < 0.01) levels were measured. As concerns the dopaminergic system, individually housed rats increased both dopamine (DA) synthesis and turnover as revealed by higher DOPAC (p < 0.01) and HVA (p < 0.05) metabolites without modification of DA levels. Moreover, in individually housed rats, corticosterone (p < 0.01) and prolactin (p < 0.05) mean levels were higher than in the control group. |
| Databáze: | OpenAIRE |
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