Effect of Multimodal Drugs Infiltration on Postoperative Pain in Split Laminectomy of Lumbar Spine
| Autor: | Patarawan Woratanarat, Chaiwat Kraiwattanapong, Vanlapa Arnuntasupakul, Nantida Langsanam, Gun Keorochana, Rungthiwa Kantawan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Epinephrine Visual analogue scale medicine.medical_treatment law.invention Pharmacotherapy Patient satisfaction Double-Blind Method Randomized controlled trial law medicine Humans Pain Management Orthopedics and Sports Medicine Anesthetics Local Aged Pain Measurement Aged 80 and over Pain Postoperative Lumbar Vertebrae Morphine business.industry Anti-Inflammatory Agents Non-Steroidal Laminectomy Middle Aged Low back pain Oswestry Disability Index Treatment Outcome Anesthesia Drug Therapy Combination Female Neurology (clinical) medicine.symptom business Anesthesia Local Follow-Up Studies medicine.drug |
| Zdroj: | Spine. 45:1687-1695 |
| ISSN: | 1528-1159 0362-2436 |
| DOI: | 10.1097/brs.0000000000003679 |
| Popis: | STUDY DESIGN A randomized, double-blinded controlled trial. OBJECTIVE This study tested the effect of single-dose wound infiltration with multiple drugs for pain management after lumbar spine surgery. SUMMARY OF BACKGROUND DATA Patients undergoing spine surgery often experience severe pain especially in early postoperative period. We hypothesized that intraoperative wound infiltration with multiple drugs would improve outcomes in lumbar spine surgery. METHODS Fifty-two patients who underwent one to two levels of spinous process splitting laminectomy of lumbar spine, were randomized into two groups. Infiltration group received intraoperative wound infiltration of local anesthetics, morphine sulfate, epinephrine, and nonsteroidal anti-inflammatory drugs at the end of surgery, and received patient-controlled analgesia (PCA) postoperatively. The control group received only PCA postoperatively. The primary outcome measures were amount of morphine consumption and visual analogue scale (VAS) for pain. The secondary outcome measures were Oswestry Disability Index (ODI), Roland-Morris Low Back Pain and Disability Questionnaire (RMDQ), patient satisfaction, length of hospital stay, and side effects. RESULTS A total of 49 patients (23 patients for local infiltration group, and 26 patients for control group) were analyzed. There were statistically significant [P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|