Is Left Ventricular Hypertrophy Regression Important? Does the Tool Used to Detect It Matter?
Autor: | Robert W Biederman, Wadih Nadour |
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Rok vydání: | 2009 |
Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism Left ventricular hypertrophy Imaging modalities Left ventricular mass Risk Factors Internal medicine Internal Medicine medicine Humans cardiovascular diseases Antihypertensive Agents Review Paper Framingham Risk Score medicine.diagnostic_test business.industry Magnetic resonance imaging Gold standard (test) medicine.disease Magnetic Resonance Imaging Regression Treatment Outcome Cardiovascular Diseases Echocardiography Cardiology Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine business |
Zdroj: | J Clin Hypertens (Greenwich) |
ISSN: | 1751-7176 1524-6175 |
DOI: | 10.1111/j.1751-7176.2009.00137.x |
Popis: | Left ventricular hypertrophy (LVH) has been demonstrated to define an adverse cardiovascular prognosis. However, due to poor noninvasive tools in which to accurately define LVH, the clinical manifestations dictate an inexact manner in which to either initiate therapy or to gauge the success of LVH regression. Herein, the authors define the current state of imaging modalities available to interrogate LVH and its regression, but concentrating chiefly on the “gold standard” of cardiovascular magnetic resonance imaging (CMR). The authors review the data demonstrating the importance of LVH regression. Additionally, they highlight the strengths and weaknesses of CMR via several pinnacle studies that demonstrate the ease, efficiency, and accuracy of this new noninvasive reproducible and available tool to relatively inexpensively delineate LVH. Finally, upon pharmacologic administration of an antihypertensive regimen, the authors, for the first time, define a goal of left ventricular mass reduction (in grams) for echocardiography and CMR based in part on Framingham data aiming at improving cardiovascular risk. |
Databáze: | OpenAIRE |
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