| Popis: |
The principles of operation, methods of standardization and calibration of an instrument for recording the dye dilution curves and for the automatic quantitative estimation of the arterial concentration of T-1824 is described. The sensitivity of the recording system appears to be adequate for recording several consecutive dye dilution curves when small quantities of dye, viz., 0.2 to 0.3 mg./kg. per injection, are used. Eighty-one comparisons were made between the dye concentration values computed automatically and those obtained by calculation. A close correlation between the results obtained by both methods in normal subjects and in patients with various cardiovascular anomalies was observed. The results reported here, and others to be published separately in a paper on determination of cardiac output, indicate that the method described allows quantitative estimation of the dye concentration in the circulating arterial blood. |
