Meconium testing for cocaine metabolite: prevalence, perceptions, and pitfalls
| Autor: | Bruce Bernstein, Diane B. Longobucco, Stephen Fishman, Fouad Boctor, Sherwood C. Lewis, Sally Rosengren, Edward Cooke |
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| Rok vydání: | 1993 |
| Předmět: |
Meconium
medicine.medical_specialty Pediatrics Urban Population Substance-Related Disorders Nurses Prenatal care Sensitivity and Specificity chemistry.chemical_compound Cocaine Pregnancy medicine Prevalence Birth Weight Humans Obstetrics business.industry Infant Newborn Obstetrics and Gynecology Prenatal Care medicine.disease Public assistance Multigravidity Suburban Population Pregnancy Complications Substance Abuse Detection Exact test chemistry Benzoylecgonine Gestation Female business |
| Zdroj: | American journal of obstetrics and gynecology. 168(5) |
| ISSN: | 0002-9378 |
| Popis: | OBJECTIVES: We determined the prevalence of prenatal cocaine use in a racially mixed sample of urban and suburban mothers and correlated its use with maternal demographics and newborn measurements. STUDY DESIGN: Meconium from 621 consecutive newborns delivered at two university-affiliated urban hospitals were assayed for benzoylecgonine. Maternal and infant characteristics were linked anonymously with the results. Statistical analysis included t tests, Fisher's exact test, Duncan's multiple range analysis, and analysis of covariance, with a value of p RESULTS: We found that 3.4% of meconium samples had benzoylecgonine levels exceeding 0.1 µg/ml. Its presence was statistically correlated with maternal and neonatal characteristics. A nurse's opinion of cocaine use was correct 22% of the time. CONCLUSIONS: Prenatal cocaine use was statistically associated with multiparity, multigravidity, late-onset and clinic-based prenatal care, public assistance, nonwhite race, and low academic achievement. A nurse's opinion was a poor predictor of maternal cocaine use. Cocaine-exposed infants were significantly smaller, and this correlated best with nonwhite background. |
| Databáze: | OpenAIRE |
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