Tumor budding and poorly-differentiated cluster in prognostication in Stage II colon cancer
| Autor: | Kui Fat Chan, Victor Wai Kwan Lee |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Oncology
Adult medicine.medical_specialty macromolecular substances Stage ii Adenocarcinoma Disease-Free Survival Pathology and Forensic Medicine Resection 03 medical and health sciences 0302 clinical medicine Tumor budding Internal medicine medicine Humans Survival analysis Aged Neoplasm Staging Retrospective Studies Aged 80 and over business.industry Poorly differentiated hemic and immune systems Retrospective cohort study Cell Biology Middle Aged Prognosis 030220 oncology & carcinogenesis Colonic Neoplasms 030211 gastroenterology & hepatology Colon adenocarcinoma Neoplasm Grading Neoplasm Recurrence Local business Colorectal Neoplasms Stage ii colon cancer |
| Zdroj: | Pathology, research and practice. 214(3) |
| ISSN: | 1618-0631 |
| Popis: | Comparison between tumor budding (TB) and poorly-differentiated clusters (PDC) for prognostication in Stage II colon cancer was not extensively studied in literature. In this retrospective study, we assessed TB (according to the consensus statement in 2016) and PDC in 135 Stage II colon adenocarcinoma resection specimens. Counting of TB and PDC was performed on HE 73% (Bd2); 52% (Bd3), p = 0.001) (DSS for PDC: 88% (Grade 1); 72% (Grade 2); 61% (Grade 3), p = 0.021). Survival curves of Stage II colon cancer could be further stratified by TB and PDC (log-rank tests: TB p |
| Databáze: | OpenAIRE |
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