Scanning Electron Microscopic Study of the Airways in Normal Children and in Patients with Cystic Fibrosis and Other Lung Diseases
| Autor: | Peter Ingram, Wisseman Cl, Philip C. Pratt, J. P. Mastin, Alexander Spock, David L. Simel, John D. Shelburne |
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| Rok vydání: | 1984 |
| Předmět: |
Adult
Lung Diseases Male Pathology medicine.medical_specialty Bronchiole Adolescent Cystic Fibrosis Scanning electron microscope Bronchi Biology Cystic fibrosis Pathology and Forensic Medicine medicine Humans In patient Cilia Child Lung Bronchiectasis Microvilli Cilium Infant Anatomy respiratory system medicine.disease Mucus Pulmonary Alveoli medicine.anatomical_structure Child Preschool Pediatrics Perinatology and Child Health Microscopy Electron Scanning Female |
| Zdroj: | Pediatric Pathology. 2:47-64 |
| ISSN: | 0277-0938 |
| DOI: | 10.3109/15513818409041187 |
| Popis: | Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were used to examine pulmonary tissue from 9 patients with cystic fibrosis (CF), 12 patients with diseases other than CF, and from two surgically resected specimens with no known airways disease. A region of the human airways, the transition zone, was observed between the end of the terminal bronchiole and the type II alveolar cell lining of the respiratory bronchioles. This region was lined predominantly by nonciliated bronchiolar (NCB) cells. Patients with CF exhibited indistinct transition zones, epidermoid metaplasia, large dilated bronchial glands, copious surface mucus, alveolar destruction, and unusual microvilli; no single lesion specific for cystic fibrosis was identified. |
| Databáze: | OpenAIRE |
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