Tobacco smoke exposure and the risk of childhood acute lymphoblastic leukemia and acute myeloid leukemia

Autor: Zhang Ruijuan, Liu Xiue, Zhang Jianhua, Wang Meifang, Yang Linhua, Zheng Zhuanzhen, Dong Chunxia
Rok vydání: 2019
Předmět:
Zdroj: Medicine
ISSN: 1536-5964
0025-7974
DOI: 10.1097/md.0000000000016454
Popis: Objective: Tobacco smoke contains carcinogens known to damage somatic and germ cells. In this study, we investigated the effect of tobacco smoking on the risk of childhood acute lymphoblastic leukemia (ALL) and myeloid leukemia (AML). Methods: Information about tobacco smoking exposures of the mother before, during, and after pregnancy was collected via PubMed, Embase, and Web of Science databases through November 5, 2018. We performed to evaluate the association between smoking exposure and the risk of childhood ALL and AML. Study selection, data abstraction, and quality assessment were performed by 2 independent reviewers. Random effects models were used to obtain summary odds ratios (ORs) and 95% confidence intervals (CIs). Results: Nineteen case–control studies of childhood leukemia (age
Databáze: OpenAIRE