Stereological studies of desmosomes in ichthyosis vulgaris
| Autor: | H Elsayed-Ali, S.P. Barton, Ronald Marks |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Ichthyosis X-Linked Adolescent Dermatology Biology Ichthyosis Vulgaris Desmosome medicine Stratum corneum Humans Child integumentary system Ichthyosis Cell Membrane Desmosomes Middle Aged medicine.disease medicine.anatomical_structure Female Abnormal desquamation Normal skin Extracellular Space Ichthyosis vulgaris |
| Zdroj: | The British journal of dermatology. 126(1) |
| ISSN: | 0007-0963 |
| Popis: | Standardized stereological methods were performed on biopsies from three subjects with normal skin and from three patients with autosomal dominant and three with autosomal recessive sex-linked ichthyosis to determine the relative numbers and dimensions of desmosomes. The results showed an increase in the persistence of desmosomes in the stratum corneum in both ichthyotic groups. This suggests a pathogenetic role for desmosomes in the abnormal desquamation of the two types of ichthyosis vulgaris. |
| Databáze: | OpenAIRE |
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