Transmissibility of the Influenza Virus during Influenza Outbreaks and Related Asymptomatic Infection in Mainland China, 2005-2013

Autor: Xixing Zhang, Yelan Li, Tianmu Chen, Jing Yang, Zhi Xie, Tao Chen, Ruchun Liu, Tian Bai, Faming Chen, Shuilian Chen, Yuelong Shu, Wenfei Zhu, Min Zhang, Cuiling Xu, Y. Chen, Zhiyu Wang, Dayan Wang, Lijie Wang
Rok vydání: 2016
Předmět:
RNA viruses
0301 basic medicine
Viral Diseases
Influenza Viruses
Veterinary medicine
lcsh:Medicine
Social Sciences
Pathology and Laboratory Medicine
medicine.disease_cause
Animal Diseases
Disease Outbreaks
Geographical Locations
0302 clinical medicine
Sociology
Zoonoses
Medicine and Health Sciences
Influenza A virus
030212 general & internal medicine
lcsh:Science
Schools
Multidisciplinary
Transmission (medicine)
Population size
H1N1
Orthomyxoviridae
Infectious Diseases
Medical Microbiology
Viral Pathogens
Population Surveillance
Viruses
Swine Influenza
Seasons
Pathogens
medicine.symptom
Research Article
Mainland China
China
medicine.medical_specialty
Asia
Infectious Disease Control
Biology
Microbiology
Asymptomatic
Education
Animal Influenza
03 medical and health sciences
Influenza
Human
medicine
Humans
Microbial Pathogens
Biology and life sciences
Public health
lcsh:R
Organisms
Outbreak
Models
Theoretical
Influenza
Influenza A virus subtype H5N1
030104 developmental biology
People and Places
lcsh:Q
Zoology
Orthomyxoviruses
Demography
Zdroj: PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0166180 (2016)
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0166180
Popis: We collected 2768 Influenza-like illness emergency public health incidents from April 1, 2005 to November 30, 2013reported in the Emergency Public Reporting System. After screening by strict inclusion and exclusion criteria, there were 613 outbreaks analyzed with susceptible-exposed-infectious/asymptomatic-removed model in order to estimate the proportion of asymptomatic individuals (p) and the effective reproduction number (Rt). The relation between Rt and viral subtypes, regions, outbreak sites, populations, and seasons were analyzed. The mean values of p of different subtypes ranged from 0.09 to 0.15, but could be as high as up to 0.94. Different subtypes, provinces, regions, and sites of outbreak had statistically significantly different Rt. In particular, the southern region also manifested different Rt by affected population size and seasonality. Our results provide China and also the rest of the world a reference to understand characteristics of transmission and develop prevention and control strategies.
Databáze: OpenAIRE
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