Odontogenic myxosarcoma of the jaw in a dog

Autor: E. M. Martín-Suárez, Rafael Zafra, José Andrés Moreno Pérez, M.M. Granados, Alba Galán, Juan M. Domínguez, R. J. Gómez
Rok vydání: 2007
Předmět:
Zdroj: ResearcherID
ISSN: 0042-4900
Popis: TUMOURS in the mouth are common in dogs and cats, con-stituting 3 per cent to 6 per cent of all tumours in these species (Harvey and Emily 1993). Mouth tumours can be differentiated into odontogenic (most commonly benign) and non-odon-togenic (most commonly malignant) tumours. Three cases of odontogenic myxoma have been reported in the veterinary literature: in a horse (Chandra and others 1999), a primate (Shalev and others 1980) and a dog (Gupta and others 2005). However, odontogenic myxosarcoma has not been described. In human beings, odontogenic myxoma is more common, and 150 cases have been reported (Burt and Zawkowski 1995); odontogenic myxosarcoma is rare, and few cases have been described (Lamberg and others 1984, Pahl and others 2000).In dogs, myxosarcomas have been found in a variety of locations. Although these tumours have a similar anatomi-cal distribution to that of myxomas, the relationship between these two tumours is uncertain, due largely to the few studies that have characterised the morphological features of myxo-sarcomas (Maitra and others 2003). The transformation of the benign variant to the malignant variant of the tumour has not been described. Such transformations have been reported for fibromas to fibrosarcomas in human beings (Chan and others 1997). This short communication describes the investigation and treatment of an odontogenic myxosarcoma in a dog.A 14-year-old male Teckel was referred to the Veterinary Hospital of the University of Cordoba. The dog had an irregular mass on the right mandible (Fig 1) involving the region from the canine tooth to the second molar. The owner reported that he had first noticed the mass 12 months previ-ously, but in the past month the mass had grown quickly; the animal was lethargic and had halitosis and blood in its saliva. The mass had been partly resected four months previously at another clinic, and the referring veterinarian indicated that the dog had been treated systemically with corticosteroids (1 mg/kg prednisolone given orally once daily) without any improvement of the clinical signs until presentation to the hospital. The dog’s drinking and eating habits were normal or only slightly reduced. After the corticosteroid treatment had begun, the dog had shown polydipsia and polyuria but therapy did not improve the dog’s condition. The mandibular lymph nodes were not enlarged.Haematological analysis revealed normochromic and normocytic anaemia (2·4 10x12 red blood cells/l, normal range 5 x 10
Databáze: OpenAIRE
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