Polyunsaturated Fatty Acids and Cardiovascular Health
| Autor: | Amy E. Binkoski, Penny M. Kris-Etherton, Kari D Hecker |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
Heart disease Linoleic acid Medicine (miscellaneous) Biology Proinflammatory cytokine Linoleic Acid chemistry.chemical_compound Polyunsaturated fat Dietary Fats Unsaturated Risk Factors Internal medicine medicine Humans chemistry.chemical_classification Clinical Trials as Topic Nutrition and Dietetics Cholesterol food and beverages Fatty acid medicine.disease Epidemiologic Studies Oxidative Stress Endocrinology Postprandial chemistry Cardiovascular Diseases Fatty Acids Unsaturated Cytokines lipids (amino acids peptides and proteins) Cell Adhesion Molecules Polyunsaturated fatty acid |
| Zdroj: | Nutrition Reviews. 62:414-426 |
| ISSN: | 1753-4887 0029-6643 |
| DOI: | 10.1111/j.1753-4887.2004.tb00013.x |
| Popis: | Epidemiologic studies have shown a beneficial association between polyunsaturated fatty acid (PUFA), specifically linoleic acid (C18:2, n-6), intake and cardiovascular disease morbidity and mortality. Clinical studies have shown that n-6 PUFAs have the most potent cholesterol-lowering effects of the individual fatty acid classes, and emerging evidence suggests that PUFAs have favorable effects on postprandial lipemia. However, some studies suggest that high intakes of linoleic acid may have adverse effects on proinflammatory cytokines and adhesion molecules. Research is needed to establish the optimal level of dietary PUFAs that maximally affects the greatest number of health risk factors. |
| Databáze: | OpenAIRE |
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