Epidemiology and pathology of oral squamous cell carcinoma in a multi-ethnic population: Retrospective study of 154 cases over 7 years in Qatar
| Autor: | Adham Ammar, Orwa Elaiwy, Moustafa Alkhalil, Walid El Ansari |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Surgical resection margin evaluation
medicine.medical_specialty Population Ethnic group Multi-ethnic 03 medical and health sciences 0302 clinical medicine Tongue Internal medicine Squamous cell carcinoma Epidemiology medicine Basal cell education Head and neck cancer Cancer och onkologi education.field_of_study business.industry Oral cancer Cancer Retrospective cohort study General Medicine medicine.disease stomatognathic diseases medicine.anatomical_structure Cancer and Oncology 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery Cross-sectional Study business |
| Zdroj: | Annals of Medicine and Surgery |
| ISSN: | 2049-0801 |
| Popis: | Background Oral cancer (OC) is a neoplastic process of the oral cavity that has high mortality and significant effects on patients’ aesthetics. The majority of OC is oral squamous cell carcinoma (OSCC) and resection remains the most frequent treatment. Recurrence is the main cause of tumor-related mortality. Material and methods A retrospective review of patients’ charts at Hamad Medical Corporation examined 154 adults who were diagnosed as OSCC and referred to the national head and neck cancer multi-disciplinary team meetings between 2012 and 2018. The data extracted was demographic, pathologic and clinical. All patients with oral cavity tumors other than squamous cell carcinoma were excluded. Results Males comprised the majority of the sample, mean age was 46.93 years. Tongue was the most common location. The majority of the patients were diagnosed at early stages, and a small subset of patients had histologically-proven local recurrence. Conclusion The young male predominance of OSCC patients in Qatar is unprecedented worldwide. Most patients were non-Qataris, mainly from South Asia. Loss of follow-up was a challenge in assessing the long-term outcomes of OSCC. Our findings suggest the need for a more vigilant surveillance approach to oral lesions particularly in male South-Asian patients, as well as improving the follow-up strategies. Highlights • Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer. • There is no published data about OSCC in Qatar, despite its ethnically diverse population. • We reviewed the charts of all OSCC adult patients in Qatar between 2012- 2018 and studied multiple parameters. • Results showed unprecedented young male predominance, mainly South Asian expats. Loss of follow-up was a major limitation. • Our findings suggest the need for more vigilant surveillance to oral lesions particularly in male South-Asians. |
| Databáze: | OpenAIRE |
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