Using drugs with immunomodulatory properties for the treatment of adenomyosis
| Autor: | V Zaporozhan, O Khait |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Endometriosis Obstetrics and Gynecology medicine.disease Gastroenterology Endometrial hyperplasia Pathogenesis Immune system medicine.anatomical_structure Hysteroscopy Internal medicine medicine Adenomyosis Bone marrow business Laparoscopy |
| Zdroj: | The Journal of the American Association of Gynecologic Laparoscopists. 1:S17 |
| ISSN: | 1074-3804 |
| Popis: | Based on the statement that immune system disorders play an important role in the pathogenesis of endometriosis, we evaluated a new method of treatment. This approach permitted subsequent administration of noretisteron acetate and myelopid (polypeptide compound from the bone marrow of mammals) for the treatment of 63 women with adenomyosis and endometrial hyperplasia. In total, 30 women were given noretisteron only; 28, noretisteron and myelopid; and 5 myelopid only. All patients were managed by HSG, hysteroscopy, laparoscopy, and the study of their hormonal and immune systems. A follow-up between 6 and 9 months after treatment revealed total pain relief in 29 patients, and partial relief in 4, who received myelopid. In this group, normal endometrium appeared in 21 (63.6%) cases with regression of endometriosis in 19 (57.5%). This therapeutic strategy significantly improved the results in comparison to the results of treatment with noretisteron acetate only. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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