A Catheter-Related Bloodstream Infection by Brevibacterium casei in a Child with Acute Myeloid Leukemia: Case Report and Literature Review
Autor: | Mayo Ueda, Kozo Nagai, Shinobu Murakami, Hisamichi Tauchi, Kyoko Moritani, Mariko Eguchi, Fumihiro Ochi, Hitoshi Miyamoto, Minenori Eguchi-Ishimae |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
medicine.drug_class medicine.medical_treatment Antibiotics Case Report medicine.disease_cause Meropenem Pediatrics RJ1-570 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Brevibacterium casei 0303 health sciences 030306 microbiology business.industry Myeloid leukemia General Medicine Catheter Staphylococcus aureus Vancomycin business 030217 neurology & neurosurgery Central venous catheter medicine.drug |
Zdroj: | Case Reports in Pediatrics, Vol 2021 (2021) Case Reports in Pediatrics |
ISSN: | 2090-6811 2090-6803 |
Popis: | The most common organisms isolated from pediatric catheter-related bloodstream infections (CRBSIs) are Gram-positive cocci, such as coagulase-negative staphylococci and Staphylococcus aureus. There are few formal reports of Brevibacterium casei infection and even fewer reports of CRBSI due to this Gram-positive rod. Here we report the first case of CRBSI due to B. casei in an 8-year-old girl with acute myeloid leukemia in Japan. The isolate exhibited decreased susceptibility to ß-lactam antibiotics. Antimicrobial therapy with meropenem and vancomycin, in addition to the removal of central venous catheter line, consequently led to a significant clinical improvement of the patient’s symptoms. A literature review found available clinical courses in 16 cases (4 pediatric cases including our case) of B. casei infection. Our case and those in literature suggested that B. casei infection often occurs in patients with indwelling central venous catheters; the literature review further suggested that removal of central venous catheters is required in most cases. Special attention should be paid to the detection of opportunistic infections due to Brevibacterium spp. in immunocompromized children who are using a central venous catheter. |
Databáze: | OpenAIRE |
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