Body Image Perception in Acromegaly Is Not Associated with Objective Acromegalic Changes but Depends on Depressive Symptoms
| Autor: | Richard Frohner, Sandra Rutz, Guenter K. Stalla, Caroline Sievers, Robert P Kosilek, Christina Dimopoulou, Jochen Schopohl, Sarah M. Leistner, Harald Schneider, Marcus Ising |
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| Rok vydání: | 2016 |
| Předmět: |
Adenoma
Male Pediatrics medicine.medical_specialty Body image perception Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Comorbidity Disease Pituitary neoplasm Severity of Illness Index 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Endocrinology Surveys and Questionnaires Internal medicine Severity of illness Acromegaly Body Image medicine Humans Cognitive Dysfunction Pituitary Neoplasms Cognitive decline Cognitive impairment Psychiatry Depressive symptoms Depression (differential diagnoses) Psychiatric Status Rating Scales business.industry Depression Endocrine and Autonomic Systems Cognition Middle Aged medicine.disease Female business Psychology 030217 neurology & neurosurgery |
| Zdroj: | Neuroendocrinology. 105:115-122 |
| ISSN: | 1423-0194 0028-3835 |
| DOI: | 10.1159/000448519 |
| Popis: | Objective: Diagnosis of acromegaly is delayed up to 10 years after disease onset despite obvious external/objective changes such as bone and soft tissue deformities. We hypothesized that a lack of subjective perception of the disease state, possibly mediated by psychiatric or cognitive alterations, might contribute to the delayed initiation of a diagnostic workup. Design: Cross-sectional study. Methods: We investigated perceived body image by standardized questionnaires (FKB-20: Fragebogen zum Körperbild; FBeK: Fragebogen zur Beurteilung des eigenen Körpers) in 81 acromegalic patients and contrasted them to (a) a clinical control group of 60 patients with nonfunctioning pituitary adenomas (NFPA) who lack severe facial and physical alterations and (b) healthy controls. We further evaluated body image in relation to objective acromegalic changes as judged by medical experts and psychiatric pathology, e.g. depression and cognitive impairment. Results: Patients with acromegaly did not lack subjective perception of the disease state; they showed more negative body image, less vitality, more insecurity/paresthesia and more accentuation of the body compared to normal controls. NFPA patients differed from acromegalic patients only in the ‘vital body dynamics' scale of the FKB-20, although they hardly exhibit any physical/bodily changes. Depression correlated with worse body image. No associations were found between body image and objective acromegalic changes as judged by medical experts, cognitive decline or treatment status. Conclusions: Negative body image in acromegalic patients is unrelated to their objective appearance and similar to those of NFPA patients without major bodily changes. Depression, but not cognitive decline or treatment status, contributes to negative body image. |
| Databáze: | OpenAIRE |
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