The emerging role of gut microbiota in cardiovascular diseases
| Autor: | Sanjeev S. Mukherjee, Soumya Patra, Arindam Pandey, Rana Rathod Roy, Dilip Kumar, Somnath Dey, Rabin Chakraborty |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
RD1-811
Review Article Gut microbiota Type 2 diabetes 030204 cardiovascular system & hematology Gut flora Bioinformatics digestive system Short-chain fatty acids 03 medical and health sciences 0302 clinical medicine Diabetes mellitus medicine Humans Diseases of the circulatory (Cardiovascular) system Obesity cardiovascular diseases 030212 general & internal medicine biology business.industry Diabetes medicine.disease biology.organism_classification Gastrointestinal Microbiome Cardiovascular diseases Diabetes Mellitus Type 2 RC666-701 Hypertension Dysbiosis Surgery Cardiology and Cardiovascular Medicine business |
| Zdroj: | Indian Heart Journal, Vol 73, Iss 3, Pp 264-272 (2021) Indian Heart Journal |
| ISSN: | 0019-4832 |
| DOI: | 10.1016/j.ihj.2021.04.008 |
| Popis: | There is mounting evidence which suggests the involvement of gut microbiota dysbiosis in the pathogenesis of various cardiovascular diseases (CVD) and associated risk states such as hypertension, type 2 diabetes, obesity and dyslipidaemia, atherosclerosis, heart failure and atrial fibrillation. The current review comprehensively summarizes the various pathogenetic mechanisms of dysbiosis in these conditions and discusses the key therapeutic implications. Further deeper understanding of the pathogenetic links between CVD and gut microbiota dysbiosis can aid in the development of novel microbiota-based targets for the management of CVDs. |
| Databáze: | OpenAIRE |
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