Lysophospholipid receptors in cell signaling
| Autor: | Khalilov Em, T. I. Torkhovskaya, O. M. Ipatova, T. S. Zakharova, M. M. Kochetova |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
G protein Cell Biology Models Biological Biochemistry Receptors G-Protein-Coupled chemistry.chemical_compound Sphingosine Cell surface receptor Lysophosphatidic acid medicine Humans Sphingosine-1-phosphate Receptor G protein-coupled receptor General Medicine Cell biology medicine.anatomical_structure Receptors Lysophospholipid chemistry Female lipids (amino acids peptides and proteins) Lysophospholipids Signal transduction Signal Transduction |
| Zdroj: | Biochemistry (Moscow). 72:125-131 |
| ISSN: | 1608-3040 0006-2979 |
| Popis: | There is increasing evidence that different phospholipids are involved in regulation of various cell processes and cell-cell interactions. Lysophospholipids (lysophosphatidic acid, lysophosphatidylcholine) and a number of lysosphingolipids play particular roles in these regulations. Their effects are mediated by specific G-protein-coupled receptors. G-Protein coupled signal transduction to the cell nucleus involving a chain of intracellular protein kinases induces the main effects in cells--growth, proliferation, survival, or apoptosis. This review summarizes recent data on various groups of lysophospholipid receptors and their cell signal transduction pathways. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|