Antimutagenic and antioxidant activity of the essential oils of Citrus sinensis and Citrus latifolia
| Autor: | Javier Espinosa-Aguirre, Julia D. Toscano-Garibay, Jaime Sánchez-Navarrete, Javier Flores-Estrada, Mario Adán Moreno-Eutimio, Myriam Arriaga-Alba, Nancy Jannet Ruiz-Pérez, M. Mendoza-García, Marisela González-Avila |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Salmonella typhimurium Citrus Antioxidant medicine.drug_class DPPH medicine.medical_treatment Antibiotics lcsh:Medicine Apoptosis Antioxidants Article Ames test 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology Cell Line Tumor medicine Oils Volatile Humans lcsh:Science Multidisciplinary Traditional medicine Superoxide Plant Extracts lcsh:R Antimutagenic Agents 04 agricultural and veterinary sciences beta Carotene 040401 food science HaCaT 030104 developmental biology chemistry Mutation lcsh:Q Reactive Oxygen Species Citrus × sinensis Citrus sinensis |
| Zdroj: | Scientific Reports Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017) |
| ISSN: | 2045-2322 |
| Popis: | The essential oils of Citrus sinensis and Citrus latifolia showed antimycotic activity against Candida spp. isolated from the oral cavity; they are neither mutagenic on the Ames test nor cytotoxic. Their main components are R-(+)-limonene, β-thujene, α-myrcene and γ-terpinene. The aim of this work was to evaluate their antimutagenic and antioxidant capacities. Antimutagenic properties were evaluated against MNNG and ENNG on S. typhimurium TA100; against 2AA on strain TA98 and in front of 4NQO and NOR on strain TA102. Both were antimutagenic against MNNG (p C. latifolia was antimutagenic against ENNG (p C. sinensis and of 22–71% for C. latifolia. Both were antioxidant compared with BHT in β-carotene bleaching assay and were able to decreased apoptosis in HaCat cells stimulated with H2O2. The levels of intracellular superoxide ion were lower in the presence of both oils. In conclusion, the essential oils of C. sinensis and C. latifolia are antimutagenic against at least three types of mutagens and have antioxidants properties. |
| Databáze: | OpenAIRE |
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